My Interests

I am interested in understanding how species respond to environmental change. Certain environmental conditions are beneficial while others are harmful to animals. Trying to understand what species will be tolerant or intolerant to particular environmental conditions is crucial for effective species management and environmental regulations in the face of climate change.

I am a proponent for open science and use an open access online lab notebook as well as GitHub to publicly share my research and support reproducibility.

I am currently a Postdoctoral Scholar working with Dr. Steven Roberts in the School of Aquatic and Fishery Sciences at the University of Washington and Dr. Mackenzie Gavery at the NOAA Northwest Fisheries Science Center in Seattle Washington.

Current Research

Projects are listed chronologically starting with the most recent. A full list of my work can be seen in the Publications section.

Unraveling the genomic response of triploid pacific oysters to temperature stress

How does ocean warming affect gene regulation Pacific Oysters (Crassostrea gigas)?

Shellfish farmers induce triploidy in their oyster seed through a variety of methods, effectively duplicating the genome and preventing the energtic investment in gametes (reproductive tissue). As a result, triploid oysters grow faster than diploids and put on more 'meat', helping to increase production speed, efficieny, and food quality. However, little is currently known regarding the effects of genome duplication on the physiological processes that regulate temperature tolerance in invertebrates. In collaboration with Dr. Steven Roberts (UW) and Dr. Mackenzie Gavery (NOAA), the goal of this project is to generate genome-wide gene expression and DNA methylation datasets from diploid and triploid oysters. Changes in gene expression and differentially methylated regions among experimental and control groups could indicate an epigenetic gene regulatory response driven by environmental fluctuations. These results provide insight into regulatory regions sensitive to methylation modification that underlie important physiological responses to environmental change, and add could result in genomic criteria for family selection during future oyster production.

Contact

Email:
   mngeorge [at] uw [dot] edu

Office:
   University of Washington
   School of Aquatic and Fishery Sciences
   1122 NE Boat Street, FTR 234
   Seattle, WA 98105, USA

Mailing address:
   Matthew George
   University of Washington
   1122 NE Boat Street Room 116
   Seattle, WA 98105, USA